) Describe in detail the DNA damage response (DDR) pathway activated by double-strand breaks. Include the roles of ATM, ATR, p53, BRCA1/2, and CHK1/CHK2. b) Compare and contrast homologous recombination (HR) and non-homologous end joining (NHEJ) with respect to: Molecular mechanisms Cell-cycle phase specificity Fidelity and biological consequences c) Explain how defects in DNA repair […]
When you engage in intense exercise, your muscles require a lot of energy quickly. However, your body’s oxygen supply might not be sufficient to meet this demand. In such cases, your muscle cells resort to anaerobic respiration to generate energy. During anaerobic respiration, your muscle cells convert glucose into energy without using oxygen. This process
What is the byproduct of anaerobic respiration in muscle cel… Read More »
) Describe in detail the DNA damage response (DDR) pathway activated by double-strand breaks. Include the roles of ATM, ATR, p53, BRCA1/2, and CHK1/CHK2. b) Compare and contrast homologous recombination (HR) and non-homologous end joining (NHEJ) with respect to: Molecular mechanisms Cell-cycle phase specificity Fidelity and biological consequences c) Explain how defects in DNA repair