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biology question

) Describe in detail the DNA damage response (DDR) pathway activated by double-strand breaks. Include the roles of ATM, ATR, p53, BRCA1/2, and CHK1/CHK2. b) Compare and contrast homologous recombination (HR) and non-homologous end joining (NHEJ) with respect to: Molecular mechanisms Cell-cycle phase specificity Fidelity and biological consequences c) Explain how defects in DNA repair

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